| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-548 | |
| Phytochemical name or plant extracts | Hyacinthus orientalis extract | |
| PMID | 33805000 | |
| Literature evidence | Results of this study showed that H. orientalis L. has promising anticancer and immunomodulatory activities. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Hydroalcoholic extract, n-hexane fraction | |
| Source of phytochemicals or plant Extracts | Hyacinthus orientalis | |
| Geographical availability | Iraq, Lebanon-Syria, Palestine, Turkey | |
| Plant parts | Whole plant | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | Hydroalcoholic extract: 0.95 ± 0.07 mg/mL against MCF-7 6.12 ± 0.1 mg/ml against T47D n-Hexane fraction: 2.23 ± 1.5 mg/mL against MCF-7 0.59 ± 0.02 mg/ml against T47D | |
| Potency | Results showed that hydroalcoholic extract and n-hexane fraction were highly effective in apoptosis induction. | |
| Cell line/ mice model | Balb/C mice, MCF-7, T47D, EMT6/P | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:536789-1 | |
| Safety | Variable degrees of inhibition were observed in MCF-7, T47D, EMT6, and VERO cell lines with lower toxicity toward VERO cells |