| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1238 | |
| Phytochemical name or plant extracts | Horminone | |
| PMID | 29451710 | |
| Literature evidence | The individual compounds (1, 3 - 8) were screened for cytotoxic activity, using the sulforhodamine B bioassay (SRB) method. | |
| IUPAC name | (4bS,8aS,10R)-1,10-dihydroxy-4b,8,8-trimethyl-2-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthrene-3,4-dione | |
| Phytochemicals’ class or type of plant extracts | Diterpenoid | |
| Source of phytochemicals or plant Extracts | Salvia deserta | |
| Geographical availability | Altay, Kazakhstan, Kirgizstan, Tadzhikistan, Uzbekistan, West Siberia, Xinjiang | |
| Plant parts | Root | |
| Other cancers | Breast cancer, Lung cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 23.624±1.812 µM against MDA-MB-231 34.833±0.922 µM against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | A549, MDA-MB-231, KB, KB-VIN, and MCF-7 | |
| Additional information | NA | |
| PubChem ID | 2751795 | |
| Additional PMIDs | 21615011 32920364 29451710 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:456094-1 | |
| Safety | NA |