| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-2100 | |
| Phytochemical name or plant extracts | Heteroclitalactone D | |
| PMID | 16557460 | |
| Literature evidence | Phytochemical investigations of the stem of Kadsura heteroclita (Roxb) Craib (Schizandraceae) resulted in the isolation and structure elucidation of six new triterpenoidal compounds named heteroclitalactones A-E (1-5) as well as heteroclic acid (6) and heteroclitalactone F (7), which was isolated for the first time from a natural source, and the six known compounds schisanlactone E (8), cycloartenone (9), schisandronic acid (10), nigranoic acid (11), changnanic acid (12) and schisanlactone B (13), respectively. | |
| IUPAC name | [(9R,13S,16S,17R,18S)-16-[(1R)-1-hydroxy-1-[(2R)-5-methyl-6-oxo-2,3-dihydropyran-2-yl]ethyl]-8,8,13,17-tetramethyl-6-oxo-7-oxatetracyclo[10.7.0.03,9.013,17]nonadeca-1(12),2,4,10-tetraen-18-yl] acetate | |
| Phytochemicals’ class or type of plant extracts | Triterpenoid | |
| Source of phytochemicals or plant Extracts | Kadsura heteroclita | |
| Geographical availability | Assam, Bangladesh, Borneo, Cambodia, China South-Central, China Southeast, East Himalaya, Hainan, India, Laos, Malaya, Myanmar, Sri Lanka, Sumatera, Taiwan, Thailand, Vietnam | |
| Plant parts | Stem | |
| Other cancers | Breast cancer, Cervical cancer, Leukemia | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 52 μM against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | Bel-7402, BGC-823, MCF-7, HL-60 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:554576-1 | |
| Safety | NA |