| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-2185 | |
| Phytochemical name or plant extracts | Helianthella quinquenervis extract | |
| PMID | 23194772 | |
| Literature evidence | The cytotoxic activity was assayed against three cell lines HT-29 (Colon adenocarcinoma), MCF-7 (Breast carcinoma), A-549 (Lung carcinoma) and only the extract of Helianthella quinquenervis possessed significant activity against the MCF-7 cell line. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Crude extract | |
| Source of phytochemicals or plant Extracts | Helianthella quinquenervis | |
| Geographical availability | Arizona, Colorado, Idaho, Mexico Northeast, Mexico Northwest, Montana, Nevada, New Mexico, Oregon, South Dakota, Wyoming | |
| Plant parts | NA | |
| Other cancers | Breast cancer, Lung cancer, Colon cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | The cytotoxic activity was assayed against three cell lines HT-29 (Colon adenocarcinoma), MCF-7 (Breast carcinoma), A-549 (Lung carcinoma) and only the extract of Helianthella quinquenervis possessed significant activity against the MCF-7 cell line. | |
| Cell line/ mice model | MCF-7, A549, HT-29 | |
| Additional information | The results of the quantitative study indicated that the extracts derived from five species (Malmea depressa, Heliopsis longipes, Datura lanosa, Cnidosculus tehuacanensis and Helianthella quinquenervis) possessed significant antiseptic properties, therefore supporting the ethnomedical uses of these species. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:211960-1 | |
| Safety | NA |