| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-383 | |
| Phytochemical name or plant extracts | Hedeoma drummondii extract | |
| PMID | 20406139 | |
| Literature evidence | Phenolic acids isolated from poleo have significant antiproliferative effects with caffeic acid the most potent. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Methanolic extract | |
| Source of phytochemicals or plant Extracts | Mexican poleo | |
| Geographical availability | Alabama, Arizona, California, Colorado, Kansas, Mexico Northeast, Mexico Northwest, Montana, Nebraska, Nevada, New Mexico, North Dakota, Oklahoma, South Dakota, Texas, Utah, Wyoming | |
| Plant parts | Aerial parts | |
| Other cancers | Breast cancer, Cervical Cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 176.4±4.5 µg/mL against MCF-7 | |
| Potency | Phenolic acids isolated from poleo have significant antiproliferative effects with caffeic acid the most potent. This evidence suggests that herbal poleo tea may have chemopreventive properties. | |
| Cell line/ mice model | MCF-7, HeLa | |
| Additional information | The methanolic extract, polar fractions, and major antioxidant compounds of the Mexican herbal tea obtained from aerial parts of H. drummondii ("poleo") showed antiproliferative effects against the cancer cell lines MCF-7 (human breast) and HeLa (human cervix). | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:447626-1 | |
| Safety | NA |