| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1926 | |
| Phytochemical name or plant extracts | Hebecarposide C | |
| PMID | 29660562 | |
| Literature evidence | Interestingly, hebecarposides C, D, G, and K selectively inhibited the proliferation of HL-60 and SMMC-7721 cell lines, and hebecarposides C and D showed significant anti-proliferative activities against A-549 cell lines than the positive control, cis-platin. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Triterpenoid | |
| Source of phytochemicals or plant Extracts | Lyonia ovalifolia var hebecarpa | |
| Geographical availability | Assam, Bangladesh, Cambodia, China North-Central, China South-Central, China Southeast, East Himalaya, Hainan, Japan, Laos, Malaya, Myanmar, Nepal, Pakistan, Taiwan, Thailand, Tibet, Vietnam, West Himalaya | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer, Lung cancer, Leukemia, Liver cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 22.15 ± 1.02 μM against MCF-7 | |
| Potency | While, hebecarposides C (3) and H (7) exhibited more potent inhibitory activities against the proliferation of MCF-7 (IC50 ¼ 22.15 ± 1.02 and 27.74 ± 1.29 mM, respectively) than the positive control (IC50 ¼ 35.02 ± 2.17 mM). | |
| Cell line/ mice model | SMMC-7721, HL-60, SW480, MCF-7, and A-549 | |
| Additional information | Exhibits more potent anti-proliferative activities against MCF-7 than cis-platin | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:60447937-2 | |
| Safety | NA |