| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1828 | |
| Phytochemical name or plant extracts | Hawaiinolide A | |
| PMID | 24882446 | |
| Literature evidence | Compound 1 showed significant cytotoxicity against a small panel of five human tumor cell lines, A549, T24, HeLa, HCT116, and MCF-7. | |
| IUPAC name | (2aS,2bS,4aR,5S,8aS,8bR,10aS)-5-ethenyl-2b-hydroxy-2a,8b-dimethyl-6-methylidene-tetradecahydro-2H-phenanthro[2,1-b]oxete-2,3-dione | |
| Phytochemicals’ class or type of plant extracts | Diterpenoid lactones | |
| Source of phytochemicals or plant Extracts | Paraconiothyrium hawaiiense | |
| Geographical availability | China | |
| Plant parts | NA | |
| Other cancers | Breast cancer, Lung cancer, Cervical Cancer, Bladder cancer, Colon cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 7.43 ± 1.6 μM against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | A549, T24, HeLa, HCT116, and MCF-7 | |
| Additional information | Exhibits cytotoxicity against A549, T24, HeLa, HCT116, and MCF-7 cell lines | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | NA | |
| Safety | NA |