| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-670 | |
| Phytochemical name or plant extracts | Grammatophyllum speciosum extract | |
| PMID | 34646091 | |
| Literature evidence | This study demonstrates the novel effect of G. speciosum as an antiproliferative via suppression of the AKT/β-catenin-dependent pathway. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Ethanolic extract | |
| Source of phytochemicals or plant Extracts | Grammatophyllum speciosum | |
| Geographical availability | Borneo, Jawa, Laos, Malaya, Myanmar, Sulawesi, Sumatera, Thailand, Vietnam | |
| Plant parts | Pseudobulb | |
| Other cancers | Breast cancer | |
| Target gene or protein | AKT, β-catenin | |
| Gene or Protein evidence | The level of phosphorylated AKT and β-catenin was suppressed by GSE treatment. | |
| Target pathways | AKT/β-catenin-dependent pathway | |
| IC50 | NA | |
| Potency | This study demonstrates the novel effect of G. speciosum as an antiproliferative via suppression of the AKT/β-catenin-dependent pathway. | |
| Cell line/ mice model | MCF-7 | |
| Additional information | Noncytotoxic concentrations of GSE significantly suppressed the proliferation of MCF-7 cells. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:636310-1 | |
| Safety | NA |