| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-343 | |
| Phytochemical name or plant extracts | Glyceryl 1-monopalmitate | |
| PMID | 34074230 | |
| Literature evidence | One of the isolated compounds, namely glyceryl 1-monopalmitate showed highly promising effect against the MCF-7 cells with (IC50 = 19.78 µM) compared to 5-FU (26.98 µM), and it remarkably stimulated apoptotic breast cancer cell death with 31.6-fold (16.13% compared to 0.51 for the control) at pre-G1 and G2/M-phase cell cycle arrest and blocked the progression of MCF-7 cells. | |
| IUPAC name | 2,3-dihydroxypropyl hexadecanoate | |
| Phytochemicals’ class or type of plant extracts | Monoglyceride | |
| Source of phytochemicals or plant Extracts | Phyllostachys heterocycla | |
| Geographical availability | China North-Central, China South-Central, China Southeast, Taiwan | |
| Plant parts | Aerial parts | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 19.78 µM against MCF-7 | |
| Potency | Glyceryl 1-monopalmitate showed highly promising effect against the MCF-7 cells with (IC50 = 19.78 µM) compared to 5-FU (26.98 µM). | |
| Cell line/ mice model | MCF-7 | |
| Additional information | Glyceryl 1-monopalmitate significantly stimulated apoptotic breast cancer cell death with 31.6-fold by arresting cell cycle at G2/M and preG1 phases. | |
| PubChem ID | 14900 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:416011-1 | |
| Safety | NA |