| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1802 | |
| Phytochemical name or plant extracts | Genkwanin | |
| PMID | 24059652 | |
| Literature evidence | RESULTS: After confirmation of the anti-tumor activity, the 95% ethanolic extract was subjected to successive solvent partitioning to petroleum ether, dichloromethane, n-butanol, and water soluble fractions. | |
| IUPAC name | 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxychromen-4-one | |
| Phytochemicals’ class or type of plant extracts | Flavonoid | |
| Source of phytochemicals or plant Extracts | Daphne genkwa | |
| Geographical availability | China North-Central, China South-Central, China Southeast, Japan, Korea, Taiwan | |
| Plant parts | Dried flowers buds | |
| Other cancers | Breast cancer, Stomach cancer, Colorectal cancer, Lung cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | >60 μg/mL against MCF-7 >60 μg/mL against MDA-MB-231 | |
| Potency | Meanwhile, six of the compounds (daphnoretin, genkwanin, 3′-hydroxygenkwanin, tiliroside, syringaresinol, and aurantiamide acetate) showed moderate IC50 values in six cancer cell lines | |
| Cell line/ mice model | MCF-7, MDA-MB-231, Huh7, AGS, HT-29, B 16, Colo 205, A549, A2058 | |
| Additional information | NA | |
| PubChem ID | 5281617 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:831227-1 | |
| Safety | NA |