| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-352 | |
| Phytochemical name or plant extracts | Garcinia mangostana extract | |
| PMID | 23805102 | |
| Literature evidence | So far, extracts and individual xanthones have been found to induce apoptosis and inhibit proliferation on cancer cells in vitro and in vivo. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Ethanolic extract | |
| Source of phytochemicals or plant Extracts | Garcinia mangostana | |
| Geographical availability | Borneo, Malaya | |
| Plant parts | Fruits | |
| Other cancers | Breast cancer, Prostate cancer, Skin cancer, Glioma | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | In light of the interesting observations of these xanthones to modulate multiple signaling pathways it is clear that further work is required to understand its potential for health promotion and potential drug discovery. | |
| Cell line/ mice model | PC3, B16F10, MCF-7, U87 | |
| Additional information | Four xanthones, α-mangostin (1), β-mangostin (2), mangostenol (3), mangaxanthone B (4), three benzophenones, mangaphenone (5), benthamianone (6), congestiflorone (7) and one sterol, stigmasterol (8) were isolated from the stem barks of Garcinia mangostana L. and G. benthamiana (Planch. & Triana) Pipoly. | |
| PubChem ID | NA | |
| Additional PMIDs | 15158999 35049434 24555285 28108382 14698525 26892433 33545910 19839614 33094642 16508181 29116938 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:428073-1 | |
| Safety | NA |