Phytochemical Name : Ganoderiol E

Properties Information
PhytoCAT-ID PhytoCAT-1767
Phytochemical name or plant extracts Ganoderiol E
PMID 22161763
Literature evidence Among them, ganoderic acid Jc (3) displayed selective inhibitory activity against HL-60 cells (IC₅₀ = 8.30 µM), and ganoderiol E (11) exhibited selective cytotoxic activity against MCF-7 cells (IC₅₀ = 6.35 µM).
IUPAC name 3-hydroxy-17-[7-hydroxy-6-(hydroxymethyl)hept-5-en-2-yl]-4,4,10,13,14-pentamethyl-1,2,3,5,6,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-7-one
Phytochemicals’ class or type of plant extracts Triterpenoid
Source of phytochemicals or plant Extracts Ganoderma sinense
Geographical availability NA
Plant parts NA
Other cancers Breast cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 6.35 µM against MCF-7
Potency NA
Cell line/ mice model MCF-7
Additional information  NA
PubChem ID 15602280
Additional PMIDs NA
Additional sources of information NA
Safety NA