Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1767 | |
Phytochemical name or plant extracts | Ganoderiol E | |
PMID | 22161763 | |
Literature evidence | Among them, ganoderic acid Jc (3) displayed selective inhibitory activity against HL-60 cells (IC₅₀ = 8.30 µM), and ganoderiol E (11) exhibited selective cytotoxic activity against MCF-7 cells (IC₅₀ = 6.35 µM). | |
IUPAC name | 3-hydroxy-17-[7-hydroxy-6-(hydroxymethyl)hept-5-en-2-yl]-4,4,10,13,14-pentamethyl-1,2,3,5,6,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-7-one | |
Phytochemicals’ class or type of plant extracts | Triterpenoid | |
Source of phytochemicals or plant Extracts | Ganoderma sinense | |
Geographical availability | NA | |
Plant parts | NA | |
Other cancers | Breast cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 6.35 µM against MCF-7 | |
Potency | NA | |
Cell line/ mice model | MCF-7 | |
Additional information | NA | |
PubChem ID | 15602280 | |
Additional PMIDs | NA | |
Additional sources of information | NA | |
Safety | NA |