Phytochemical Name : Galium aparine extract (GA MeOH)

Properties Information
PhytoCAT-ID PhytoCAT-1872
Phytochemical name or plant extracts Galium aparine extract (GA MeOH)
PMID 27085941
Literature evidence AIM OF THE STUDY: To investigate the potential anti-proliferative and apoptotic effect of GA methanol (MeOH) extract on MCF-7 and MDA-MB-231 human breast cancer cells and MCF-10A untransformed breast epithelial cells.
IUPAC name NA
Phytochemicals’ class or type of plant extracts Methanol (MeOH) extract
Source of phytochemicals or plant Extracts Galium aparine
Geographical availability Afghanistan, Albania, Algeria, Altay, Austria, Azores, Baleares, Baltic States, Belarus, Belgium, Bulgaria, Buryatiya, Canary Is., Central European Rus, China North-Central, China South-Central, China Southeast, Chita, Corse, Cyprus, Czechoslovakia, Denmark, East Aegean Is., East European Russia, East Himalaya, Finland, France, Germany, Great Britain, Greece, Gulf States, Hungary, India, Iran, Iraq, Ireland, Irkutsk, Italy, Kirgizstan, Korea, Krasnoyarsk, Kriti, Krym, Lebanon-Syria, Libya, Madeira, Manchuria, Mongolia, Morocco, Nepal, Netherlands, North European Russi, Northwest European R, Norway, Oman, Pakistan, Palestine, Poland, Portugal, Romania, Sardegna, Saudi Arabia, Selvagens, Sicilia, South European Russi, Spain, Sweden, Switzerland, Tadzhikistan, Tibet, Tunisia, Turkey, Turkey-in-Europe, Tuva, Ukraine, Uzbekistan, Vietnam, West Himalaya, West Siberia, Yakutskiya, Yugoslavia
Plant parts NA
Other cancers Breast cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 NA
Potency Our study suggests that GA MeOH extract may have potential anti-cancer effects against breast cancer cells without impairing normal breast epithelial cells.
Cell line/ mice model MCF-7, MDA-MB-231, MCF-10A
Additional information  NA
PubChem ID NA
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:30007294-2
Safety However, it was not cytotoxic to MCF-10A breast epithelial cells.