Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1872 | |
Phytochemical name or plant extracts | Galium aparine extract (GA MeOH) | |
PMID | 27085941 | |
Literature evidence | AIM OF THE STUDY: To investigate the potential anti-proliferative and apoptotic effect of GA methanol (MeOH) extract on MCF-7 and MDA-MB-231 human breast cancer cells and MCF-10A untransformed breast epithelial cells. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Methanol (MeOH) extract | |
Source of phytochemicals or plant Extracts | Galium aparine | |
Geographical availability | Afghanistan, Albania, Algeria, Altay, Austria, Azores, Baleares, Baltic States, Belarus, Belgium, Bulgaria, Buryatiya, Canary Is., Central European Rus, China North-Central, China South-Central, China Southeast, Chita, Corse, Cyprus, Czechoslovakia, Denmark, East Aegean Is., East European Russia, East Himalaya, Finland, France, Germany, Great Britain, Greece, Gulf States, Hungary, India, Iran, Iraq, Ireland, Irkutsk, Italy, Kirgizstan, Korea, Krasnoyarsk, Kriti, Krym, Lebanon-Syria, Libya, Madeira, Manchuria, Mongolia, Morocco, Nepal, Netherlands, North European Russi, Northwest European R, Norway, Oman, Pakistan, Palestine, Poland, Portugal, Romania, Sardegna, Saudi Arabia, Selvagens, Sicilia, South European Russi, Spain, Sweden, Switzerland, Tadzhikistan, Tibet, Tunisia, Turkey, Turkey-in-Europe, Tuva, Ukraine, Uzbekistan, Vietnam, West Himalaya, West Siberia, Yakutskiya, Yugoslavia | |
Plant parts | NA | |
Other cancers | Breast cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | NA | |
Potency | Our study suggests that GA MeOH extract may have potential anti-cancer effects against breast cancer cells without impairing normal breast epithelial cells. | |
Cell line/ mice model | MCF-7, MDA-MB-231, MCF-10A | |
Additional information | NA | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:30007294-2 | |
Safety | However, it was not cytotoxic to MCF-10A breast epithelial cells. |