| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-830 | |
| Phytochemical name or plant extracts | Galangal extract (GE) | |
| PMID | 31983172 | |
| Literature evidence | OBJECTIVE: This study intends to explore the potential of galangal extract as a co-chemotherapeutic agent through the analysis of its cytotoxic and migratory effects on metastatic breast cancer cells and as an anti-ageing agent through its senescence inhibitory effect on normal fibroblast cells. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Ethanolic extract | |
| Source of phytochemicals or plant Extracts | Alpinia galanga | |
| Geographical availability | Assam, Bangladesh, Borneo, Cambodia, China South-Central, China Southeast, Hainan, Jawa, Malaya, Myanmar, Philippines, Sumatera, Thailand, Vietnam | |
| Plant parts | NA | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 135 µg/mL against 4T1 | |
| Potency | Galangal has the potential for use as a co-chemotherapeutic agent by inducing senescence in correlation with increasing intracellular ROS toward metastatic breast cancer. | |
| Cell line/ mice model | 4T1 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:795279-1 | |
| Safety | NA |