| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1013 | |
| Phytochemical name or plant extracts | Galanal A | |
| PMID | 30645035 | |
| Literature evidence | Among the isolates, compounds 4 and 5 exhibited significant antiproliferative activities against a small panel of human cancer cell lines, including lung (LK-2, A549), stomach (ECC4), breast (MCF7), cervix (HeLa), and prostate (DU145). © 2019 Wiley-VHCA AG, Zurich, Switzerland. | |
| IUPAC name | (4aS,6aS,7S,11aR,11bS)-7-hydroxy-4,4,11b-trimethyl-1,2,3,4a,5,6,7,8,11,11a-decahydrocyclohepta[a]naphthalene-6a,9-dicarbaldehyde | |
| Phytochemicals’ class or type of plant extracts | Dinorcassane Diterpenoid | |
| Source of phytochemicals or plant Extracts | Boesenbergia rotunda | |
| Geographical availability | Andaman Is., Assam, Cambodia, China South-Central, Jawa, Lesser Sunda Is., Malaya, Myanmar, Sumatera, Thailand, Vietnam | |
| Plant parts | Rhizome | |
| Other cancers | Breast cancer, Lung cancer, Stomach cancer, Cervical cancer, Prostate cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 38.6 μM against MCF-7 | |
| Potency | Among the isolates, galanals A (4) and B (5) were the most potent. | |
| Cell line/ mice model | MCF-7, LK-2, A549, ECC4, HeLa, DU145 | |
| Additional information | Exhibits significant antiproliferative activities against a small panel of human cancer cell lines, including lung (LK-2, A549), stomach (ECC4), breast (MCF7), cervix (HeLa), and prostate (DU145) | |
| PubChem ID | 3050416 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:872224-1 | |
| Safety | NA |