| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-740 | |
| Phytochemical name or plant extracts | Frangula alnus extract | |
| PMID | 32847047 | |
| Literature evidence | The current findings of this study include a novel comprehensive investigation on the polyphenol composition and anticancer effects of leaf extracts of F. alnus and P. harmala from natural populations in Saudi Arabia. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Methanolic extract | |
| Source of phytochemicals or plant Extracts | Frangula alnus | |
| Geographical availability | Albania, Algeria, Altay, Austria, Baltic States, Belarus, Belgium, Bulgaria, Central European Rus, Corse, Czechoslovakia, Denmark, East European Russia, Finland, France, Germany, Great Britain, Greece, Hungary, Iran, Iraq, Ireland, Italy, Kazakhstan, Krasnoyarsk, Krym, Morocco, Netherlands, North Caucasus, North European Russi, Northwest European R, Norway, Poland, Portugal, Romania, South European Russi, Spain, Sweden, Switzerland, Transcaucasus, Tunisia, Turkey, Turkey-in-Europe, Tuva, Ukraine, West Siberia, Xinjiang, Yugoslavia | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer, Colorectal cancer, Cervical cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 39.64 ± 3.3 µg/mL against MCF-7 | |
| Potency | F. alnus and P. harmala leaf extracts showed cytotoxic effects against Jurkat, MCF-7, HeLa, and HT-29 cancer cells using MTT and flow cytometry assays. | |
| Cell line/ mice model | Jurkat, MCF-7, HeLa, and HT-29 | |
| Additional information | The current findings of this study include a novel comprehensive investigation on the polyphenol composition and anticancer effects of leaf extracts of F. alnus and P. harmala from natural populations in Saudi Arabia. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:717344-1 | |
| Safety | NA |