| Properties | Information |
|---|---|
| PhytoCAT-ID | PhytoCAT-1885 |
| Phytochemical name or plant extracts | Flaxseed aglycone rich extracts (FSARE) |
| PMID | 27876207 |
| Literature evidence | The treatment brings about a significant decrease in super oxide dismutase (SOD) and glutathione peroxidase (GPx) activity, thereby leading to accumulation of superoxide ion and peroxide in the cells. |
| IUPAC name | NA |
| Phytochemicals’ class or type of plant extracts | Extract |
| Source of phytochemicals or plant Extracts | NA |
| Geographical availability | NA |
| Plant parts | NA |
| Other cancers | Breast cancer |
| Target gene or protein | NA |
| Gene or Protein evidence | NA |
| Target pathways | NA |
| IC50 | NA |
| Potency | SARE and FSARE were found to increase the ROS levels and modulate anti-oxidant enzymes within the cells, thereby disturbing the tightly regulated homeostasis of cancer cells and causing DNA damage. |
| Cell line/ mice model | MCF-7 and MDA-MB-231 |
| Additional information | NA |
| PubChem ID | NA |
| Additional PMIDs | NA |
| Additional sources of information | NA |
| Safety | NA |