| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-914 | |
| Phytochemical name or plant extracts | Ficus carica extracts | |
| PMID | 32454742 | |
| Literature evidence | Similarly, both extracts showed strong α-glucosidase and α-amylase inhibition activity, while the water extract had higher inhibition activity than the methanol extract against acetylcholinesterase and butyrylcholinesterase. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Methanolic extract | |
| Source of phytochemicals or plant Extracts | Ficus carica | |
| Geographical availability | Afghanistan, Cyprus, Greece, Iran, Iraq, Kriti, Lebanon-Syria, North Caucasus, Pakistan, Palestine, Tadzhikistan, Transcaucasus, Turkey, Turkmenistan, West Himalaya | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 0.081 mg/mL against MDA-MB-231 | |
| Potency | Consequently, the methanolic extract of the leaf of F. carica may be considered a potential therapeutic agent in cancer and diabetes mellitus. | |
| Cell line/ mice model | MDA-MB-231 | |
| Additional information | The methanol extract of F. carica exhibited significant anticancer activity on MDA-MB-231 cells and showed moderate antimicrobial activities against Escherichia coli and Staphylococcus aureus. | |
| PubChem ID | NA | |
| Additional PMIDs | 30100743 31814674 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:852556-1 | |
| Safety | NA |