| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1824 | |
| Phytochemical name or plant extracts | Fevicordin-A (FevA) | |
| PMID | 24776765 | |
| Literature evidence | Potential activity of fevicordin-A from Phaleria macrocarpa (Scheff) Boerl. seeds as estrogen receptor antagonist based on cytotoxicity and molecular modelling studies. | |
| IUPAC name | [(E,6R)-6-hydroxy-2-methyl-5-oxo-6-[(8S,9S,13S,14S,16R)-2,3,16-trihydroxy-4,9,13-trimethyl-11-oxo-6,7,8,12,14,15,16,17-octahydrocyclopenta[a]phenanthren-17-yl]hept-3-en-2-yl] acetate | |
| Phytochemicals’ class or type of plant extracts | Lignan | |
| Source of phytochemicals or plant Extracts | Phaleria macrocarpa | |
| Geographical availability | New Guinea | |
| Plant parts | Seeds | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 6.4 µM against MCF-7 | |
| Potency | Collectively, both the experimental and computational results indicated that FevA has potential as a candidate for an anticancer agent, which is worth promoting for further preclinical evaluation. | |
| Cell line/ mice model | MCF-7, T47D | |
| Additional information | NA | |
| PubChem ID | 70682436 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:832478-1 | |
| Safety | NA |