| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-2062 | |
| Phytochemical name or plant extracts | Ferutinin | |
| PMID | 24716944 | |
| Literature evidence | Accordingly, there is an increasing desire to discover new natural compounds with selective toxicity to combat malignancies. | |
| IUPAC name | [(3R,3aS,4S,8aR)-3-hydroxy-6,8a-dimethyl-3-propan-2-yl-1,2,3a,4,5,8-hexahydroazulen-4-yl] 4-hydroxybenzoate | |
| Phytochemicals’ class or type of plant extracts | Phytoestrogen | |
| Source of phytochemicals or plant Extracts | Ferula ovina | |
| Geographical availability | Afghanistan, Iran, Iraq, Kazakhstan, Kirgizstan, Pakistan, Saudi Arabia, Tadzhikistan, Turkmenistan, Uzbekistan, Xinjiang | |
| Plant parts | NA | |
| Other cancers | Breast cancer, Bladder cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | Alkaline comet assay and DAPI staining revealed DNA damage due to ferutinin, which was significantly (p<0.001) higher in MCF7 and TCC than HFF3 cells. | |
| Cell line/ mice model | MCF-7, TCC, HFF3 | |
| Additional information | Apoptosis induction was evidenced by PI staining and DNA laddering. Our results suggest that ferutinin could be considered as an effective anticancer agent for future in vivo and clinical experiments. | |
| PubChem ID | 354654 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:77129493-1 | |
| Safety | NA |