Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-901 | |
Phytochemical name or plant extracts | Ferula hermonis Boiss. extract | |
PMID | 31380416 | |
Literature evidence | This study also demonstrated the antitumor activity of FHRH in 9,10-dimethylbenz[α]anthracene DMBA-induced rodent mammary tumor model. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Hexane extract | |
Source of phytochemicals or plant Extracts | Ferula hermonis | |
Geographical availability | Lebanon-Syria, Turkey | |
Plant parts | Root | |
Other cancers | Breast cancer, Colon cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 18.2 μg/ml against MDA-MB-231 | |
Potency | Overall, the present study suggests that FHRH extract possesses anticancer potential which is mediated through apoptotic effects in MDA-MB-231 and LoVo cells. | |
Cell line/ mice model | MDA-MB-231/ Wistar albino rats | |
Additional information | This study also demonstrated the antitumor activity of FHRH in 9,10-dimethylbenz[α]anthracene DMBA-induced rodent mammary tumor model. The GC/MS analysis revealed the presence of 3,5-Dimethylbenzenemethanol, Alpha-Bisabolol, Alpha-pinene, Beta-pinene, and Baccatin III that have various pharmacological potentials. | |
PubChem ID | NA | |
Additional PMIDs | 22057918 15787464 | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:842303-1 | |
Safety | NA |