Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-894 | |
Phytochemical name or plant extracts | Falcarinol | |
PMID | 24269959 | |
Literature evidence | They display interesting bioactivities and hold potential as health-promoting and therapeutic agents. | |
IUPAC name | (3R,9Z)-heptadeca-1,9-dien-4,6-diyn-3-ol | |
Phytochemicals’ class or type of plant extracts | polyacetylene | |
Source of phytochemicals or plant Extracts | Chaerophyllum aureum | |
Geographical availability | Albania, Austria, Bulgaria, Czechoslovakia, France, Germany, Greece, Hungary, Iran, Italy, Krym, North Caucasus, Poland, Romania, Spain, Switzerland, Transcaucasus, Turkey, Turkey-in-Europe, Yugoslavia | |
Plant parts | NA | |
Other cancers | Breast cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | NA | |
Potency | NA | |
Cell line/ mice model | MCF-7 | |
Additional information | These findings suggest that the mechanism of the L-type calcium channel-blocking activity of falcarinol (1a) and its analogue (R)-2i might be involved in neuroprotection by falcarinol-type analogues by inhibiting calcium overload in the upstream of the signaling pathway. | |
PubChem ID | 5281149 | |
Additional PMIDs | 34319736 | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:840142-1 | |
Safety | NA |