Phytochemical Name : Extract of Centella asiatica

Properties Information
PhytoCAT-ID PhytoCAT-1344
Phytochemical name or plant extracts Extract of Centella asiatica
PMID 20162036
Literature evidence The present study evaluated the ability of methanolic extract of Centella asiatica (Linn) Urban (Umbelliferae) to induce apoptosis in different cancer cell lines.
IUPAC name NA
Phytochemicals’ class or type of plant extracts Methanolic extract
Source of phytochemicals or plant Extracts Centella asiatica
Geographical availability Andaman Is., Angola, Assam, Bangladesh, Belize, Benin, Borneo, Botswana, Burkina, Burundi, Cabinda, Cambodia, Cameroon, Cape Provinces, Cape Verde, Caprivi Strip, Caroline Is., Central African Repu, Chad, Chatham Is., China North-Central, China South-Central, China Southeast, Comoros, Congo, East Himalaya, Equatorial Guinea, Eritrea, Ethiopia, Fiji, Free State, Gabon, Gambia, Ghana, Guinea, Guinea-Bissau, Gulf of Guinea Is., India, Iran, Ivory Coast, Japan, Jawa, Kenya, Korea, KwaZulu-Natal, Laos, Lesotho, Lesser Sunda Is., Liberia, Madagascar, Malawi, Malaya, Mali, Maluku, Marianas, Marshall Is., Mauritania, Mauritius, Mozambique, Myanmar, Namibia, Nansei-shoto, Nepal, New Caledonia, New Guinea, New South Wales, New Zealand North, New Zealand South, Nicobar Is., Niger, Nigeria, Northern Provinces, Ogasawara-shoto, Pakistan, Philippines, Queensland, Rodrigues, Rwanda, Réunion, Samoa, Saudi Arabia, Senegal, Sierra Leone, Socotra, Solomon Is., Somalia, Sri Lanka, Sudan, Sulawesi, Sumatera, Swaziland, Taiwan, Tanzania, Thailand, Togo, Tonga, Transcaucasus, Uganda, Vietnam, Wallis-Futuna Is., West Himalaya, Yemen, Zambia, Zaïre, Zimbabwe
Plant parts NA
Other cancers Breast cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways This indicates that apoptosis induction by MECA involves mitochondrial pathway
IC50 NA
Potency LD50- 10 µM (MCF-7)
Cell line/ mice model MCF-7
Additional information  NA
PubChem ID NA
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:1197718-2
Safety NA