Phytochemical Name : Euphorbia szovitsii Fisch & C.A. Mey extract

Properties Information
PhytoCAT-ID PhytoCAT-1364
Phytochemical name or plant extracts Euphorbia szovitsii Fisch & C.A. Mey extract
PMID 30459240
Literature evidence Annexin V-FITC/PI assay confirmed that the extract was able to induce apoptosis in MDA-MB-231 cells.
IUPAC name NA
Phytochemicals’ class or type of plant extracts Hydroalcoholic extract
Source of phytochemicals or plant Extracts Euphorbia szovitsii Fisch & CAMey
Geographical availability Afghanistan, Iran, Iraq, Kirgizstan, Lebanon-Syria, North Caucasus, Pakistan, Palestine, Tadzhikistan, Transcaucasus, Turkey, Turkmenistan, Uzbekistan
Plant parts Aerial parts
Other cancers Breast cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways Necrosis pathway
IC50 At 24h, 48h: 76.78 µg/ml , 59.71 µg/ml against MDA-MB-231
Potency NA
Cell line/ mice model MDA-MB-231
Additional information  Moreover, treatment with the extract resulted in cell cycle arrest at G1 phase.
PubChem ID NA
Additional PMIDs 35132492
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:348424-1
Safety NA