Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1364 | |
Phytochemical name or plant extracts | Euphorbia szovitsii Fisch & C.A. Mey extract | |
PMID | 30459240 | |
Literature evidence | Annexin V-FITC/PI assay confirmed that the extract was able to induce apoptosis in MDA-MB-231 cells. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Hydroalcoholic extract | |
Source of phytochemicals or plant Extracts | Euphorbia szovitsii Fisch & CAMey | |
Geographical availability | Afghanistan, Iran, Iraq, Kirgizstan, Lebanon-Syria, North Caucasus, Pakistan, Palestine, Tadzhikistan, Transcaucasus, Turkey, Turkmenistan, Uzbekistan | |
Plant parts | Aerial parts | |
Other cancers | Breast cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | Necrosis pathway | |
IC50 | At 24h, 48h: 76.78 µg/ml , 59.71 µg/ml against MDA-MB-231 | |
Potency | NA | |
Cell line/ mice model | MDA-MB-231 | |
Additional information | Moreover, treatment with the extract resulted in cell cycle arrest at G1 phase. | |
PubChem ID | NA | |
Additional PMIDs | 35132492 | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:348424-1 | |
Safety | NA |