| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-269 | |
| Phytochemical name or plant extracts | Euphoranginone D (3) | |
| PMID | 34236840 | |
| Literature evidence | All these results suggested that 6 may serve as a promising lead for the development of novel anti-TNBC agents in the future. | |
| IUPAC name | (1S,4S,9R,10R,11S,13S,14S)-5,5,9,13-tetramethyl-12-oxapentacyclo[11.2.1.111,14.01,10.04,9]heptadecan-6-one | |
| Phytochemicals’ class or type of plant extracts | Diterpenoid | |
| Source of phytochemicals or plant Extracts | Croton kongensis | |
| Geographical availability | China South-Central, Hainan, Laos, Myanmar, Thailand, Vietnam | |
| Plant parts | Stem | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | >5 μM against MDA-MB-231 >5 μM against MDA-MB-468 >5 μM against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | MDA-MB-231, MDA-MB-468, MCF-7 | |
| Additional information | NA | |
| PubChem ID | 101926764 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:342785-1 | |
| Safety | NA |