| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-298 | |
| Phytochemical name or plant extracts | Euphopubescene | |
| PMID | 15114502 | |
| Literature evidence | Compounds 1 - 3 have been evaluated for their ability to inhibit the in vitro growth of three human tumour cell lines representing different tumour types, MCF-7 (breast adenocarcinoma), NCI-H460 (non-small cell lung cancer) and SF-268 (CNS cancer). | |
| IUPAC name | 3beta,7beta,8beta,9alpha,14alpha,15beta-hexaacetoxy-2beta H-jatropha-5 E,11 E-diene | |
| Phytochemicals’ class or type of plant extracts | Diterpenoid | |
| Source of phytochemicals or plant Extracts | Euphorbia pubescens | |
| Geographical availability | Albania, Algeria, Baleares, Canary Is., Corse, Cyprus, East Aegean Is., France, Greece, Iraq, Italy, Kriti, Lebanon-Syria, Morocco, Palestine, Portugal, Sardegna, Sicilia, Spain, Transcaucasus, Tunisia, Turkey, Turkey-in-Europe, Yugoslavia | |
| Plant parts | Whole plant | |
| Other cancers | Breast cancer, Lung cancer, Brain cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | GI50 = 72.0 ± 5.8 against MCF-7 | |
| Cell line/ mice model | MCF-7, NCI-H460, SF-268 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:347936-1 | |
| Safety | NA |