Phytochemical Name : Eugenia jambolana extract (JFE)

Properties Information
PhytoCAT-ID PhytoCAT-1728
Phytochemical name or plant extracts Eugenia jambolana extract (JFE)
PMID 19166352
Literature evidence These studies suggest that JFE may have potential beneficial effects against breast cancer.
IUPAC name NA
Phytochemicals’ class or type of plant extracts Extract
Source of phytochemicals or plant Extracts Eugenia jambolana
Geographical availability Andaman Is., Assam, Bangladesh, Cambodia, China South-Central, China Southeast, East Himalaya, Hainan, India, Jawa, Laccadive Is., Laos, Lesser Sunda Is., Malaya, Maluku, Myanmar, Nepal, Pakistan, Queensland, Sri Lanka, Sulawesi, Thailand, Vietnam
Plant parts Fruits
Other cancers Breast cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 40 µg/mL against MDA-MB-231 5.9 µg/mL against MCF-7
Potency These studies suggest that JFE may have potential beneficial effects against breast cancer.
Cell line/ mice model MDA-MB-231
Additional information  JFE supplementation significantly alleviated diet-induced obesity, insulin resistance, and liver steatosis. JFE supplementation also improved HFD-induced gut dysbiosis by restoring the ratio of Firmicutes to Bacteroidetes as revealed by 16S rDNA analyses.
PubChem ID NA
Additional PMIDs 30762938
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:594746-1
Safety NA