Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1519 | |
Phytochemical name or plant extracts | Eucalrobusone C | |
PMID | 27412352 | |
Literature evidence | Among these isolates, eucalrobusone C (3) showed significant cytotoxicity against HepG2, MCF-7, and U2OS cancer cell lines, with IC50 values less than 10 μm. | |
IUPAC name | 3-{[(1S,4S,6S,8aS)-4,8a-dimethyl-6-(prop-1-en-2-yl)-1,2,3,4,6,7,8,8a-octahydronaphthalen-1-yl]methyl}-2,6-dihydroxy-4-methoxy-5-(3-methylbutanoyl)benzaldehyde | |
Phytochemicals’ class or type of plant extracts | formyl-phloroglucinolmeroterpenoid | |
Source of phytochemicals or plant Extracts | Eucalyptus robusta | |
Geographical availability | New South Wales, Queensland | |
Plant parts | Leaves | |
Other cancers | Breast cancer, Liver cancer, Bone cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 8.99+_0.64 µM against MCF-7 | |
Potency | Shows significant cytotoxicity against HepG2, MCF-7, and U2OS cell lines, significantly blocks cell proliferation and induces cell death through apoptosis (in MCF-7 cells) | |
Cell line/ mice model | HepG2, MCF-7, and U2OS | |
Additional information | NA | |
PubChem ID | 132541818 | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:593318-1 | |
Safety | NA |