Phytochemical Name : Eucalrobusone C

Properties Information
PhytoCAT-ID PhytoCAT-1519
Phytochemical name or plant extracts Eucalrobusone C
PMID 27412352
Literature evidence Among these isolates, eucalrobusone C (3) showed significant cytotoxicity against HepG2, MCF-7, and U2OS cancer cell lines, with IC50 values less than 10 μm.
IUPAC name 3-{[(1S,4S,6S,8aS)-4,8a-dimethyl-6-(prop-1-en-2-yl)-1,2,3,4,6,7,8,8a-octahydronaphthalen-1-yl]methyl}-2,6-dihydroxy-4-methoxy-5-(3-methylbutanoyl)benzaldehyde
Phytochemicals’ class or type of plant extracts formyl-phloroglucinolmeroterpenoid
Source of phytochemicals or plant Extracts Eucalyptus robusta
Geographical availability New South Wales, Queensland
Plant parts Leaves
Other cancers Breast cancer, Liver cancer, Bone cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 8.99+_0.64 µM against MCF-7
Potency Shows significant cytotoxicity against HepG2, MCF-7, and U2OS cell lines, significantly blocks cell proliferation and induces cell death through apoptosis (in MCF-7 cells)
Cell line/ mice model HepG2, MCF-7, and U2OS
Additional information  NA
PubChem ID 132541818
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:593318-1
Safety NA