| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1353 | |
| Phytochemical name or plant extracts | Erythronium japonicum extracts | |
| PMID | 25671063 | |
| Literature evidence | CONCLUSIONS: Our results collectively indicate that Erythronium japonicum extracts inhibit the growth, adhesion, migration and invasion as well as induce the apoptosis of human breast cancer cells. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Methanolic extract, Ethanolic extract | |
| Source of phytochemicals or plant Extracts | Erythronium japonicum | |
| Geographical availability | Japan, Korea, Kuril Is., Manchuria, Sakhalin | |
| Plant parts | NA | |
| Other cancers | Breast cancer | |
| Target gene or protein | MMP2, MMP9 | |
| Gene or Protein evidence | The motility and MMP-2 and MMP-9 activities were also inhibited by both methanol and ethanol extracts. | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | NA | |
| Cell line/ mice model | MDA-MB-231 | |
| Additional information | In the present study, Erythronium japonicum extracts demonstrated antiproliferative and proapoptotic properties. In fact, the ethanol extract of Erythronium japonicum showed more antiproliferative and proapoptotic properties as well as also more effectively inhibited the invasion of MDA-MB-231 cells. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:534936-1 | |
| Safety | NA |