| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-178 | |
| Phytochemical name or plant extracts | Erycibe elliptilimba extract | |
| PMID | 17140753 | |
| Literature evidence | The results indicated that the extract fraction 3 could induce cell cycle arrest in some way. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Methanolic extract | |
| Source of phytochemicals or plant Extracts | Erycibe elliptilimba | |
| Geographical availability | Cambodia, China Southeast, Hainan, Laos, Thailand, Vietnam | |
| Plant parts | Stem | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | The ED50 value of Erycibe elliptilimba Merr. & Chun. fraction 3 was 56.07 and 30.61 microg/ml for SKBR3 and MDA-MB435, respectively. After 48 h of exposure, this fraction at a concentration of 100 microg/ml significantly reduced cell proliferation in both cancer cells. | |
| Cell line/ mice model | SKBR-3, MDA-MB-435 | |
| Additional information | In MDA-MB435 cells, cell cycle analysis showed that the herb extract fraction 3 induced the accumulation of cells in G2/M phase, whereas no significant change in cell cycle was detected in SKBR3 cells. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:267865-1 | |
| Safety | NA |