| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1506 | |
| Phytochemical name or plant extracts | Ergost-25-ene-3,6-dione,5,12-dihydroxy-,(5.alpha.,12.beta.) | |
| PMID | 34643844 | |
| Literature evidence | Hence, the present study concludes that the phytocompounds from the aqueous extract of Solanum torvum unripe fruits have the potential ability to treat breast cancer. © 2021. | |
| IUPAC name | (5R,8S,9S,10R,12R,13R,14S,17R)-17-[(2R,5R)-5,6-dimethylhept-6-en-2-yl]-5,12-dihydroxy-10,13-dimethyl-1,2,4,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthrene-3,6-dione | |
| Phytochemicals’ class or type of plant extracts | Phytocompounds | |
| Source of phytochemicals or plant Extracts | Solanum torvum | |
| Geographical availability | Bahamas, Belize, Brazil Northeast, Brazil Southeast, Cayman Is., Colombia, Costa Rica, Dominican Republic, Ecuador, El Salvador, French Guiana, Guatemala, Guyana, Haiti, Honduras, Leeward Is., Mexico Central, Mexico Gulf, Mexico Northeast, Mexico Northwest, Mexico Southeast, Mexico Southwest, Nicaragua, Panamá, Puerto Rico, Trinidad-Tobago, Venezuela, Windward Is. | |
| Plant parts | Fruits | |
| Other cancers | Breast cancer | |
| Target gene or protein | BRCA1 | |
| Gene or Protein evidence | Damage that occurs to BRCA1 by chance prevents the protein from DNA repair process and thereby increases the risk of developing tumor | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | Hence, the present study concludes that the phytocompounds from the aqueous extract of Solanum torvum unripe fruits have the potential ability to treat breast cancer. | |
| Cell line/ mice model | MCF-7 | |
| Additional information | NA | |
| PubChem ID | 91692405 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:821287-1 | |
| Safety | NA |