Phytochemical Name : Epipachysandrine-A

Properties Information
PhytoCAT-ID PhytoCAT-312
Phytochemical name or plant extracts Epipachysandrine-A
PMID 27681716
Literature evidence In addition, the isolates were examined for their ability to inhibit the migration of MDA-MB-231 cells induced by the chemokine epidermal growth factor (EGF).
IUPAC name N-[(3S,4R,5R,8S,9S,10R,13S,14S,17S)-17-[(1S)-1-(dimethylamino)ethyl]-4-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]benzamide
Phytochemicals’ class or type of plant extracts Alkaloid
Source of phytochemicals or plant Extracts Pachysandra terminalis
Geographical availability China North-Central, China South-Central, China Southeast, Japan, Sakhalin
Plant parts Whole plant
Other cancers Breast cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 5.71 ± 0.84 μM against MDA-MB-231
Potency NA
Cell line/ mice model MDA-MB-231
Additional information  NA
PubChem ID 71367060
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:353208-1
Safety NA