Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1141 | |
Phytochemical name or plant extracts | Endophytes of noni | |
PMID | 26783408 | |
Literature evidence | The cytotoxic potential of organic extracts derived from the fermented broths of individual endophytes was then tested against three major cancers that afflict humans. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Organic extract | |
Source of phytochemicals or plant Extracts | Morinda citrifoliainn | |
Geographical availability | Andaman Is., Assam, Bangladesh, Bismarck Archipelago, Borneo, Cambodia, China Southeast, Christmas I., Cocos (Keeling) Is., Hainan, India, Jawa, Kazan-retto, Laccadive Is., Lesser Sunda Is., Malaya, Maldives, Maluku, Myanmar, Nansei-shoto, New Guinea, Nicobar Is., Northern Territory, Ogasawara-shoto, Philippines, Queensland, Santa Cruz Is., Solomon Is., South China Sea, Sri Lanka, Sulawesi, Sumatera, Taiwan, Thailand, Vietnam, Western Australia | |
Plant parts | Culturable endophytic fungi resident within the healthy leaves and fruits of the plant | |
Other cancers | Breast cancer, Lung cancer, Prostate cance | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | Three of the leaf endophytes inhibited the growth of human carcinoma cell lines LU-1 (lung), PC-3 (prostate), and MCF-7 (breast) with IC50 values of ≤10 μg/mL. | |
Potency | NA | |
Cell line/ mice model | LU-1, PC-3, MCF-7 | |
Additional information | NA | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:756359-1 | |
Safety | NA |