| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-832 | |
| Phytochemical name or plant extracts | Eicosapentaenoic acid | |
| PMID | 9386867 | |
| Literature evidence | Eicosapentaenoic acid and sulphur substituted fatty acid analogues inhibit the proliferation of human breast cancer cells in culture. | |
| IUPAC name | (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoic acid | |
| Phytochemicals’ class or type of plant extracts | Omega-3 fatty acid | |
| Source of phytochemicals or plant Extracts | Alpinia oxyphylla | |
| Geographical availability | China South-Central, China Southeast, Hainan, Vietnam | |
| Plant parts | NA | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | Thus, of the two dietary polyunsaturated omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid, only eicosapentaenoic acid possesses an inhibitory effect on the proliferation of MCF-7 cells. | |
| Cell line/ mice model | MCF-7 | |
| Additional information | NA | |
| PubChem ID | 446284 | |
| Additional PMIDs | 30194562 12550055 14767544 15138577 23550153 25712053 27687127 28577869 28804463 29616321 31963198 2224849 34486791 7757957 9816126 9386867 9673380 10624705 11239764 17052999 17311938 25448730 27041742 31440598 32588470 20425756 26729084 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:795356-1 | |
| Safety | NA |