| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1517 | |
| Phytochemical name or plant extracts | Eichlerianic acid | |
| PMID | 25742723 | |
| Literature evidence | Among them, compounds 1 and 2 showed significant cytotoxicity against human cancer cell (HL-60, SMMC-7721, A-549, MCF-7 and SW480) with IC50 values of 0.007-0.095 μM, while compounds 3-5 and 10 and 11 showed moderate to no cytotoxicity (IC50 0.43 to values >40 μM). | |
| IUPAC name | 3-[(3S,3aR,5aR,6S,7S,9aR,9bR)-3-[(2S,5S)-5-(2-hydroxypropan-2-yl)-2-methyloxolan-2-yl]-6,9a,9b-trimethyl-7-prop-1-en-2-yl-1,2,3,3a,4,5,5a,7,8,9-decahydrocyclopenta[a]naphthalen-6-yl]propanoic acid | |
| Phytochemicals’ class or type of plant extracts | Diterpenoid glycoside | |
| Source of phytochemicals or plant Extracts | Aglaia odorata | |
| Geographical availability | Cambodia, China Southeast, Hainan, Laos, Malaya, Thailand, Vietnam | |
| Plant parts | Root | |
| Other cancers | Breast cancer, Colorectal cancer, Leukemia, Liver cancer, Lung cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 6.87 µM against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | HL-60, SMMC-7721, A-549, MCF-7 and SW480 | |
| Additional information | NA | |
| PubChem ID | 12315516 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:577227-1 | |
| Safety | Show acute toxicity, as given in pubchem |