Properties |
Information |
PhytoCAT-ID |
PhytoCAT-41 |
Phytochemical name or plant extracts |
E/Z-acetoside |
PMID |
17294687 |
Literature evidence |
Taken together, the novel compound 8 is effective as anti-proliferative agent against MCF-7 cells and as NO inhibitor, whereas 2 exhibited multi-functional properties as antioxidant and anti-proliferative agent against both solid tumor cell lines Hep-G2 and MCF-7 cells. |
IUPAC name |
[(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate |
Phytochemicals’ class or type of plant extracts |
Glycoside |
Source of phytochemicals or plant Extracts |
Tecoma stans |
|
Geographical availability |
Argentina Northeast, Argentina Northwest, Arizona, Bahamas, Bolivia, Cayman Is., Colombia, Costa Rica, Cuba, Dominican Republic, Ecuador, El Salvador, Florida, Guatemala, Haiti, Honduras, Jamaica, Leeward Is., Mexico Central, Mexico Gulf, Mexico Northeast, Mexico Northwest, Mexico Southeast, Mexico Southwest, Netherlands Antilles, New Mexico, Nicaragua, Panamá, Peru, Puerto Rico, Southwest Caribbean, Texas, Trinidad-Tobago, Turks-Caicos Is., Venezuela, Venezuelan Antilles, Windward Is. |
Plant parts |
Fruits and flowers |
Other cancers |
Breast cancer, Liver cancer |
Target gene or protein |
NA |
Gene or Protein evidence |
NA |
Target pathways |
NA |
IC50 |
NA |
Potency |
The extract, 2 and 8 were potent growth inhibitors of human breast carcinoma cells (MCF-7). Compound 2 is E/Z-acetoside. |
Cell line/ mice model |
Hep-G2, MCF-7 |
Additional information |
Taken together, the novel compound 8 is effective as anti-proliferative agent against MCF-7 cells and as NO inhibitor, whereas 2 exhibited multi-functional properties as antioxidant and anti-proliferative agent against both solid tumor cell lines Hep-G2 and MCF-7 cells. |
PubChem ID |
5281800 |
Additional PMIDs |
NA |
Additional sources of information |
https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:111284-1 |
Safety |
NA |