| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1337 | |
| Phytochemical name or plant extracts | Dysobinin | |
| PMID | 22277739 | |
| Literature evidence | Cedrelone (13) and dysobinin (18) showed significant cytotoxicity, and toonayunnanin B (2) and epoxyazadiradione (14), were found to be slightly cytotoxic against the above cell lines. | |
| IUPAC name | [(5R,6S,7S,9R,10R,13S,17R)-7-acetyloxy-17-(furan-3-yl)-4,4,8,10,13-pentamethyl-3-oxo-5,6,7,9,11,12,16,17-octahydrocyclopenta[a]phenanthren-6-yl] acetate | |
| Phytochemicals’ class or type of plant extracts | Triterpenoid | |
| Source of phytochemicals or plant Extracts | Toona ciliata Chisocheton siamensis | |
| Geographical availability | Toona ciliata - Assam, Bangladesh, Bismarck Archipelago, Borneo, Cambodia, China South-Central, China Southeast, East Himalaya, Hainan, India, Jawa, Laos, Lesser Sunda Is., Malaya, Maluku, Myanmar, Nepal, New Guinea, Pakistan, Philippines, Sulawesi, Sumatera, Thailand, Vietnam, West Himalaya Chisocheton siamensis - Assam, Bangladesh, Cambodia, China South-Central, China Southeast, East Himalaya, Laos, Myanmar, Thailand, Vietnam | |
| Plant parts | Leaves Seeds | |
| Other cancers | Breast cancer, Leukemia, Liver cancer, Lung cancer, Oral epidermal cancer, Colon cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 2.15 µg/mL against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | HL-60, SMMC-7721, A-549, MCF-7, SW480, NCI-H187, KB | |
| Additional information | NA | |
| PubChem ID | 181314 | |
| Additional PMIDs | 18617378 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:579299-1 https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:886780-1 | |
| Safety | NA |