| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-264 | |
| Phytochemical name or plant extracts | Dracocephalum surmandinum essential oil | |
| PMID | 20334155 | |
| Literature evidence | The essential oil of D. surmandinum and its two main constituents showed a marked antioxidant and radical scavenging activity using different model systems, including 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) and beta-carotene-linoleic acid blenching assays. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Essential oil | |
| Source of phytochemicals or plant Extracts | Dracocephalum surmandinum | |
| Geographical availability | Afghanistan, Alaska, Alberta, Altay, Amur, Arizona, Austria, Baltic States, Belarus, British Columbia, Bulgaria, Buryatiya, Central European Rus, China North-Central, China South-Central, Chita, Colorado, Connecticut, Czechoslovakia, Delaware, East European Russia, East Himalaya, France, Germany, Hungary, Idaho, Illinois, Indiana, Inner Mongolia, Iowa, Iran, Irkutsk, Italy, Japan, Kamchatka, Kazakhstan, Khabarovsk, Kirgizstan, Korea, Krasnoyarsk, Kuril Is., Labrador, Magadan, Maine, Manchuria, Manitoba, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Mongolia, Montana, Morocco, Nebraska, Nepal, Nevada, New Hampshire, New Jersey, New Mexico, New York, Newfoundland, North Carolina, North Caucasus, North Dakota, North European Russi, Northwest European R, Norway, Nova Scotia, Ohio, Ontario, Oregon, Pakistan, Pennsylvania, Poland, Primorye, Qinghai, Québec, Rhode I., Romania, Saskatchewan, South Dakota, South European Russi, Spain, Sweden, Switzerland, Tadzhikistan, Thailand, Tibet, Transcaucasus, Turkey, Turkmenistan, Tuva, Ukraine, Utah, Uzbekistan, Vermont, Washington, West Himalaya, West Siberia, West Virginia, Wisconsin, Wyoming, Xinjiang, Yakutskiya | |
| Plant parts | Aerial parts | |
| Other cancers | Breast cancer, Leukemia | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 14 µg/ml against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | MCF-7, K562 | |
| Additional information | The oil was rich in oxygenated (73.1%) and hydrocarbon (25.0%) monoterpenes including perilla aldehyde (63.4 %) and limonene (22.1%) as the major constituents. From 25 identified compounds (97.8%) in the oil of D. surmandinum perilla aldehyde (54.3%) and limonene (30.1%) were the main constituents. | |
| PubChem ID | NA | |
| Additional PMIDs | 22007732 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:331573-2 | |
| Safety | NA |