Phytochemical Name : Dichlorodiaportinol A

Properties Information
PhytoCAT-ID PhytoCAT-611
Phytochemical name or plant extracts Dichlorodiaportinol A
PMID 24914297
Literature evidence Gray and its cytotoxic activity.
IUPAC name 3-(3,3-dichloro-2,3-dihydroxy-propyl)-8-hydroxy-6- methoxy-isochromen-1-one
Phytochemicals’ class or type of plant extracts Coumarin
Source of phytochemicals or plant Extracts Myoporum bontioides
Geographical availability China Southeast, Hainan, Japan, Nansei-shoto, South China Sea, Taiwan, Vietnam
Plant parts Root
Other cancers Breast cancer, Liver cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 17.8 μg/mL against MCF-7
Potency Compound one is a new chlorine-containing isocoumarin with moderate cytotoxic activity against MCF-7 and HepG2 cell lines.
Cell line/ mice model MCF-7, HepG2
Additional information  In China, the decoction of Myoporum bontioides A. Gray is usually used as a folk medicine for antidermatosis and as antipyretic and antipsychotic agent.
PubChem ID NA
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:585264-1
Safety NA