Phytochemical Name : Demethylcryptojaponol

Properties Information
PhytoCAT-ID PhytoCAT-1240
Phytochemical name or plant extracts Demethylcryptojaponol
PMID 29451710
Literature evidence The individual compounds (1, 3 - 8) were screened for cytotoxic activity, using the sulforhodamine B bioassay (SRB) method.
IUPAC name (4aS,10aS)-5,6-dihydroxy-1,1,4a-trimethyl-7-propan-2-yl-3,4,10,10a-tetrahydro-2H-phenanthren-9-one
Phytochemicals’ class or type of plant extracts Diterpenoid
Source of phytochemicals or plant Extracts Salvia deserta
Geographical availability Altay, Kazakhstan, Kirgizstan, Tadzhikistan, Uzbekistan, West Siberia, Xinjiang
Plant parts Root
Other cancers Breast cancer, Lung cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 26.243±0.140 µM against MDA-MB-231 28.590±0.336 µM against MCF-7
Potency NA
Cell line/ mice model A549, MDA-MB-231, KB, KB-VIN, and MCF-7
Additional information  NA
PubChem ID 10403490
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:456094-1
Safety NA