Phytochemical Name : Dehydrodicatechin A

Properties Information
PhytoCAT-ID PhytoCAT-701
Phytochemical name or plant extracts Dehydrodicatechin A
PMID 26922854
Literature evidence Quercetin showed significant cytotoxic activity against HepG2 and MCF-7 cell lines with IC50 values of 4.88 and 0.87 μg/mL, respectively.
IUPAC name (8S,9R,16S,18S,27S)-9-(3,4-dihydroxyphenyl)-5,8,16,21,23-pentahydroxy-2,10,17,26-tetraoxaheptacyclo[14.11.1.01,13.03,12.06,11.018,27.020,25]octacosa-3(12),4,6(11),13,20,22,24-heptaen-15-one
Phytochemicals’ class or type of plant extracts Flavonoid
Source of phytochemicals or plant Extracts Calligonum polygonoides
Geographical availability Gulf States, Iran, Iraq, Kuwait, Lebanon-Syria, Pakistan, Palestine, Saudi Arabia, Sinai, Transcaucasus, Turkey, Yemen
Plant parts Aerial parts
Other cancers Breast cancer, Liver cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 67.09 µg/ml against MCF-7
Potency Compound 2 showed the best cytotoxic and antioxidant activity.
Cell line/ mice model MCF-7, HepG2
Additional information  NA
PubChem ID 182270
Additional PMIDs 18069236
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:693386-1
Safety NA