Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1507 | |
Phytochemical name or plant extracts | Daucosterol | |
PMID | 24459770 | |
Literature evidence | Compound 5 was the most active against the K-562 cell line (IC50 = 50.2 microg/mL), with a selectivity exceeding that of methotrexate 13.3 times. | |
IUPAC name | (2R,3R,4S,5S,6R)-2-[[(3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol | |
Phytochemicals’ class or type of plant extracts | Phytosterol | |
Source of phytochemicals or plant Extracts | Pterospermum yunnanense | |
Geographical availability | China South-Central | |
Plant parts | Leaves and twigs | |
Other cancers | Breast cancer, Oral cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | NA | |
Potency | All compounds inhibited proliferation of MCF-7 (human breast adenocarcinoma) and BHY (human oral squamous carcinoma) cells in a concentration?dependent manner | |
Cell line/ mice model | MCF-7 and BHY | |
Additional information | NA | |
PubChem ID | 5742590 | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:824821-1 | |
Safety | NA |