| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-263 | |
| Phytochemical name or plant extracts | Cyperus longus extract | |
| PMID | 26893742 | |
| Literature evidence | Our results demonstrated that two of the constituents of Cyperus longus, viridiflorol and longiverbenone, should be investigated further as possible promising chemotherapeutic agents in cancer treatment. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Methanolic extract, Dichloromethane (CH2Cl2) extract, Ethyl acetate (EtOAc) and water fractions | |
| Source of phytochemicals or plant Extracts | Cyperus longus | |
| Geographical availability | Afghanistan, Albania, Algeria, Angola, Austria, Azores, Baleares, Bangladesh, Belgium, Benin, Botswana, Bulgaria, Burkina, Cameroon, Canary Is., Cape Provinces, Cape Verde, Caprivi Strip, Central African Repu, Chad, Corse, Cyprus, Djibouti, East Aegean Is., Egypt, Ethiopia, France, Free State, Germany, Great Britain, Greece, Hungary, India, Iran, Iraq, Italy, Kazakhstan, Kenya, Kirgizstan, Kriti, Krym, KwaZulu-Natal, Lebanon-Syria, Lesotho, Madagascar, Madeira, Mali, Morocco, Mozambique, Namibia, Nepal, Niger, Nigeria, North Caucasus, Northern Provinces, Oman, Pakistan, Palestine, Portugal, Romania, Sardegna, Saudi Arabia, Senegal, Sicilia, Socotra, Somalia, South European Russi, Spain, Sudan, Swaziland, Switzerland, Tadzhikistan, Tanzania, Togo, Transcaucasus, Tunisia, Turkey, Turkey-in-Europe, Turkmenistan, Uganda, Uzbekistan, Western Sahara, Yemen, Yugoslavia, Zambia, Zimbabwe | |
| Plant parts | NA | |
| Other cancers | Breast cancer, Prostate cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | After 48h: CH2Cl2 fraction - 25.34±2.01 µg/ml against MCF-7 EtOAc fraction - 35.2±2.69 µg/ml against MCF-7 Methanol extract - 64.64±1.64 µg/ml) against MCF-7 | |
| Potency | The most effective fraction in the MCF7 cell line was the CH2Cl2 fraction (IC50 after 48 h, 25.34±2.01). The EtOAc fraction (IC50 after 48 h, 35.2±2.69) and the methanol extract (IC50 after 48 h, 64.64±1.64) were also found to be effective. | |
| Cell line/ mice model | PC3, MCF-7 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:330932-2 | |
| Safety | NA |