Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1091 | |
Phytochemical name or plant extracts | Cynanchum paniculatum extract | |
PMID | 34122605 | |
Literature evidence | Our data suggested that CP has anticancer potential on various breast cancer cells through different mechanisms and is specifically effective in inhibiting the migration of the triple negative MDA-MB-231. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Aqueous extract | |
Source of phytochemicals or plant Extracts | Cynanchum paniculatum | |
Geographical availability | E. Asia - China, Japan. | |
Plant parts | NA | |
Other cancers | Breast cancer | |
Target gene or protein | MMP2 | |
Gene or Protein evidence | CP inhibited the migration of the two Her2(-) cells, and this correlated with MMP-2 regulation. | |
Target pathways | NA | |
IC50 | NA | |
Potency | Our data suggested that CP has anticancer potential on various breast cancer cells through different mechanisms and is specifically effective in inhibiting the migration of the triple negative MDA-MB-231. | |
Cell line/ mice model | MDA-MB-231, MCF-7, ZR-75-1 | |
Additional information | NA | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://pfaf.org/user/Plant.aspx?LatinName=Cynanchum+paniculatum | |
Safety | NA |