Phytochemical Name : Cuscutamine

Properties Information
PhytoCAT-ID PhytoCAT-1089
Phytochemical name or plant extracts Cuscutamine
PMID 15095143
Literature evidence Along with cuscutamine ( 1) and kaempferol ( 4), 6 was tested in the transient luciferase reporter assay and was found to have different luciferase inducing activity characteristics from the other compounds.
IUPAC name (5S,11bS)-3-oxo-1,2,5,6,11,11b-hexahydroindolizino[8,7-b]indole-5-carboxylic acid
Phytochemicals’ class or type of plant extracts Alkaloid
Source of phytochemicals or plant Extracts Cuscuta chinensis
Geographical availability Afghanistan, Arizona, Assam, Bangladesh, China North-Central, China South-Central, China Southeast, Eritrea, Ethiopia, Ghana, India, Inner Mongolia, Iran, Iraq, Japan, Kazakhstan, Kirgizstan, Korea, Madagascar, Manchuria, Mexico Central, Mexico Northeast, Mexico Northwest, Mexico Southwest, Mongolia, Nansei-shoto, Nepal, New Mexico, New South Wales, Northern Territory, Pakistan, Primorye, Qinghai, Queensland, Saudi Arabia, Socotra, Sri Lanka, Sudan, Tadzhikistan, Taiwan, Texas, Thailand, Tibet, Turkmenistan, Utah, Uzbekistan, Vietnam, West Himalaya, Western Australia, Xinjiang
Plant parts Seeds
Other cancers Breast cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 NA
Potency The compound significantly stimulated not only MCF-7 cell proliferation but also T47D human breast cancer cells at a concentration of 10 microM.
Cell line/ mice model MCF-7, T47D
Additional information  NA
PubChem ID 6995636
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:267360-1
Safety NA