| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-183 | |
| Phytochemical name or plant extracts | Cuphea aequipetala Extracts | |
| PMID | 31275985 | |
| Literature evidence | This extract was able to induce accumulation of cells on G1 phase of the cell cycle, moreover, it was able to induce DNA fragmentation and increase the activity of caspase-3 in B16F10 cells. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Extract | |
| Source of phytochemicals or plant Extracts | Cuphea aequipetala | |
| Geographical availability | Guatemala, Honduras, Mexico Central, Mexico Gulf, Mexico Northeast, Mexico Northwest, Mexico Southeast, Mexico Southwest | |
| Plant parts | Aerial parts | |
| Other cancers | Breast cancer, Larynx cancer, Colon cancer, Prostate cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | In conclusion, the in vitro data showed that both C. aequipetala extracts were able to induce cytotoxicity through the apoptosis pathway in B16F10 cells | |
| IC50 | NA | |
| Potency | Preliminarily, the extracts of C. aequipetala can be stated as a potential therapeutic option in cancer. | |
| Cell line/ mice model | MCF-7, HepG2, B16F10, HCT-15, DU145 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:275405-2 | |
| Safety | NA |