Phytochemical Name : Crovatin

Properties Information
PhytoCAT-ID PhytoCAT-657
Phytochemical name or plant extracts Crovatin
PMID 11914970
Literature evidence Croblongifolin showed a significant cytotoxicity against various human tumor cell lines including HEP-G2, SW620, CHAGO, KATO3 and BT474.
IUPAC name methyl 7-(furan-3-yl)-4-methyl-8,10,12-trioxapentacyclo[11.3.1.01,11.05,9.05,16]heptadecane-17-carboxylate
Phytochemicals’ class or type of plant extracts Diterpene
Source of phytochemicals or plant Extracts Croton oblongifolius
Geographical availability Djibouti, Eritrea, Ethiopia, Gulf States, India, Oman, Pakistan, Palestine, Saudi Arabia, Sinai, Socotra, Somalia, Sudan, Yemen
Plant parts Stem 
Other cancers Breast cancer, Liver cancer, Colorectal cancer, Lung cancer, Stomach cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 >12 μM against BT474
Potency NA
Cell line/ mice model HEP-G2, SW620, CHAGO, KATO3, BT-474
Additional information  NA
PubChem ID 495412
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:60464928-2
Safety NA