| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1537 | |
| Phytochemical name or plant extracts | Cratochinone B | |
| PMID | 31820330 | |
| Literature evidence | Compounds 2, 5, and 7 showed significant cytotoxic effects against all cell lines with IC50 values in the range of 0.91-9.93 μM, while 10 exhibited cytotoxicity against the KB, HeLa S-3, and HT-29 cells with IC50 values of 7.39, 6.07, and 8.11 μM, respectively. | |
| IUPAC name | 1-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-hydroxy-2,8-dimethoxy-7-(4-methylpent-3-en-1-yl)-9H-xanthen-9-one | |
| Phytochemicals’ class or type of plant extracts | Xanthone | |
| Source of phytochemicals or plant Extracts | Cratoxylum cochinchinense | |
| Geographical availability | Andaman Is., Borneo, Cambodia, China South-Central, China Southeast, Laos, Malaya, Myanmar, Nicobar Is., Philippines, Sumatera, Thailand, Vietnam | |
| Plant parts | Root | |
| Other cancers | Breast cancer, Liver cancer, Colon cancer, Mouth cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 1.76±0.06 µM against MCF-7 | |
| Potency | Compounds 2, 5, and 7 showed significant cytotoxic effects against all cell lines with IC50 values in the range of 0.91-9.93 µM. Compound 2 is Cratochinone B | |
| Cell line/ mice model | KB, HeLa S-3, HT-29, MCF-7 and Hep G2 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:433054-1 | |
| Safety | NA |