| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-234 | |
| Phytochemical name or plant extracts | Crataegus gracilior extract | |
| PMID | 31635496 | |
| Literature evidence | B. Phipps) stems and leaves induce cell death on breast cancer cells. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Petroleum ether extract, Ethanolic extract, Aqueous extract | |
| Source of phytochemicals or plant Extracts | Crataegus gracilior | |
| Geographical availability | Guatemala, Mexico Central, Mexico Gulf, Mexico Northeast, Mexico Southeast, Mexico Southwest | |
| Plant parts | Leaves and stem | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | Petroleumether extract - 43.9 μg/mL against MDA-MB-231, 47.6 μg/mL against MCF-7 | |
| Potency | Results suggest that he cytotoxic and pro-apoptotic effects of the petroleum ether extract of C. gracilior could be exerted by the joint activity of β-sitosterol and tocopherol, possibly in combination with of other minor compounds. | |
| Cell line/ mice model | NA | |
| Additional information | Two compounds reportedly having cytotoxic activity were identified by mass spectrometry in the petroleum extract of C. gracilior: β-sitosterol and tocopherol. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:314978-2 | |
| Safety | NA |