| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-180 | |
| Phytochemical name or plant extracts | Cornus mas extract | |
| PMID | 26320443 | |
| Literature evidence | Our results indicated that a hydro-alcoholic extract of CM possesses high potency to inhibit proliferation of different tumor cells in a dose independent manner, suggesting that an optimal biological dose is more important and relevant than a maximally tolerated one. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Hydroalcoholic extract | |
| Source of phytochemicals or plant Extracts | Cornus mas | |
| Geographical availability | Albania, Austria, Belgium, Bulgaria, Czechoslovakia, East Aegean Is., France, Germany, Hungary, Italy, Krym, Lebanon-Syria, North Caucasus, Romania, Switzerland, Transcaucasus, Turkey, Turkey-in-Europe, Ukraine, Yugoslavia | |
| Plant parts | Fruits | |
| Other cancers | Breast cancer, Lung cancer, Ovarian cancer, Prostate cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | <5μg/ml against MCF-7 | |
| Potency | The mean growth inhibition was 81.8%, 81.9%, 81.6% and 79.3% in SKOV3, MCF-7, PC-3 and A549 cells, respectively. | |
| Cell line/ mice model | SKOV3, MCF-7, PC-3, A549 | |
| Additional information | Our results indicated that a hydro-alcoholic extract of CM possesses high potency to inhibit proliferation of different tumor cells in a dose independent manner, suggesting that an optimal biological dose is more important and relevant than a maximally tolerated one. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:271612-1 | |
| Safety | NA |